I think it has a lot of potential. Some A/B/O fics write Betas as asexual, which makes sense -- like worker bees, they handle the everyday tasks while the more volatile orientations are caught up in reproductive imperatives.

I've done a lot with hormones and pheromones in some of my writing. It can be fun to explore. The Blueshift Troupers has a whole running thread about affinity -- the way people react to each other and to biotech, which works similar to the 'good chemistry' of finding a compatible mate. Except it isn't just sexual, it spans different kinds of relationships.

I am generally interested in seeing people dig deeper into social dynamics, human bonding, types of relationships, etc. -- especially in areas where people are usually distracted by sex. Take that out, and you can see other things better.